Due to a mutation on the melanocortin -1 receptor, natural red heads have an increased sensitivity to thermal pain and a decrease response to anesthesia. This information may not be news to red heads, but it is something that health care practitioners need to be aware of! Extra care must be taken to insure a comfortable procedure!
My recommendations: Take 600mg ibuprofen or 500 mg acetaminophen 1 hour before your dental appointment. Antianxiety medication like diazepam may be necessary to achieve profound anesthesia.
Remember to express your concern with your dentist so that your appointment will be drama free!
Liem EB, Joiner TV, Tsueda K, Sessler DI. Anesthesiology. 2005Mar;10(3):509-14.
Liem EB, Lin CM, Suleman MI, Doufas AG, Gregg RG, Veauthier JM, Loyd G, Sessler DI. Anesthesiology. 2004Aug;101(2):279-83.